Low theophylline level
Web1 jul. 1997 · Serum theophylline level was determined after 5 days of treatment, and the initial dosage was appropriately decreased in case of serum theophylline level >15 ng/mL. 8 15. Follow-up. The patients were enrolled in a long-term phase and were seen at the outpatient clinic every 3 months. WebFor example; concomitant administration of CYP450 enzyme inducers phenytoin, or rifampicin, result in low theophylline plasma levels, thus higher doses may be required. Decreased clearance of theophylline may be seen with liver disease, and heart failure, and therefore appropriate dose reduction and monitoring of plasma levels is required .
Low theophylline level
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Web8 jun. 2000 · However, antiinflammatory benefits appear to occur at lower plasma theophylline levels (< 10 mg/L), and the incidence of any adverse effects is minimized. Two studies have demonstrated that low-dose theophylline added to inhaled steroids was equally efficacious when compared with increasing the dose of inhaled steroids, in … WebPotentially serious hypokalaemia may result from beta-2 agonist therapy. Adverse effects can occur with plasma theophylline concentrations of 10 mg/L to 20 mg/L. However, a …
WebTheophylline is an oral bronchodilator with a narrow therapeutic window, used in the treatment of conditions such as asthma and chronic obstructive pulmonary disease … WebTherapeutic drug monitoring. In most individuals, a plasma-theophylline concentration of 10–20 mg/litre (55–110 micromol/litre) is required for satisfactory bronchodilation, …
Web31 aug. 2024 · low potassium level--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or … Web1 jan. 2003 · Patients with pulmonary hypertension had earlier disease onset, lower forced expiratory flow of 25-75%, lower arterial oxygen tension and lower pre-6MWT SpO2 (p < 0.05), older age, and lower SpO2 ...
WebTheophylline reduces inflammation or irritation in lungs and airways, relaxes smooth muscles in the airways and digestive system, and stimulates the central nervous system. But theophylline can be harmful in high doses or if the theophylline level in your blood is too high, so your healthcare provider may want to test your level of theophylline.
Web3 feb. 2024 · Theophylline distributes poorly into body fat, therefore mg/kg doses should be calculated on the basis of lean (ideal) bodyweight. Plasma theophylline concentrations should ideally be maintained between 5 and 12 micrograms/ml. A plasma level of 5 micrograms/ml probably represents the lower level of clinical effectiveness. how to know the pf balanceWeb1 jun. 2024 · There also appears to be a dose-response for the effects on the diaphragm contractility where blood levels > 10 μg/mL are more efficacious. 36 However theophylline is dosed today primarily for its ant-inflammatory effects, and maintaining blood levels of theophylline as low as 5 μg/mL is efficacious in patients with asthma and COPD. 42 By … how to know the percentage of a numberWebHeparin level (Low Molecular Weight Heparin) After first dose (pediatrics) After third dose (adults) 3 doses (adults) 1 dose (pediatrics) Daily dosing (adults): 1-2 unit/mL Q12H … how to know the pf balance through smsWebDecreased effect/increased toxicity: Changes in diet may affect the elimination of theophylline; ... ncreased theophylline level: Allopurinol (>600 mg/day), beta-blockers, calcium channel blockers, carbamazepine, CHF, cimetidine, ciprofloxacin, cor pulmonale, corticosteroids, ... how to know the password using cmdWebCheck Plasma Theophylline Level within 4-6 hours of commencement Re-Check Plasma Theophylline Level after any dose adjustment, within 4-6 hours. Check Plasma Theophylline Level every 24 hours, even if levels stable. Result mg/L Symptoms & Dose Tolerance Action < 9.9 Not controlled current dosage is tolerated ↑ rate by 25% 10 to … joseph woll maple leafsWebTheophylline therapeutic level. Therapeutic Levels for theophylline 1: For children: 5 to 15 mcg/mL; For adults: 10 to 20 mcg/mL; Toxic serum concentration: greater than 20 mcg/mL 6. Toxic doses of theophylline can be as low as 7.5 mg/kg 7. When taken orally, 80% to 100% of theophylline is absorbed in the gastrointestinal tract. joseph woll nhl.comWebPremature infants have very low rates of theophylline elimination. Conversely, theophylline elimination is more rapid among cigarette smokers. In combination with other clinical data, monitoring serum theophylline levels may provide the physician with useful information to aid in adjusting patient dosage to achieve optimal therapeutic effect while … how to know the password of phpmyadmin