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Naphthalene mechanism of toxicity

Witryna1 maj 2014 · Naphthalene (NA) is a ubiquitous pollutant to which humans are widely exposed. NA causes tumors in rats and mice, and has been classified as a Possible Human Carcinogen. The mechanism of NA carcinogenicity is believed to involve repeated cycles of NA-induced acute lung injury and repair. A prerequisite for NA … Naphthalene poisoning (or mothball poisoning) is a form of poisoning that occurs when naphthalene is ingested. Severe poisoning can result in haemolytic anaemia. Naphthalene was introduced in 1841 by Rossbach as an antiseptic to counteract typhoid fever. Although naphthalene was widely used … Zobacz więcej Until the late 1950s coal tar was the principal source of naphthalene. From 1981 to 1983 the U.S. National Institute for Occupational Safety and Health found over 100,000 workers were potentially exposed to … Zobacz więcej Treatment of naphthalene toxicity usually follows the same treatments involved for haemolytic anaemia, which involves a series of blood … Zobacz więcej According to the International Agency for Research on Cancer, naphthalene is possibly carcinogenic to humans (Group 2B), as there is inadequate evidence in humans for the … Zobacz więcej

1-Naphthylacetic acid C12H10O2 - PubChem

WitrynaNaphthalene was not toxic to fiddler crabs under these conditions at any concentration up to 16.69 ppm. No chemically induced phase shift in the circadian rhythm of naphthalene exposed crabs occurs. ... {Effects and mechanism of action of naphthalene, a petroleum-derived polycyclic aromatic hydrocarbon, on black pigment … Witryna1 wrz 2009 · Ingestional naphthalene mothball poisoning leading to prolonged haemolysis and methaemoglobinaemia can present with diagnostic and therapeutic challenges. A 19-year-old woman ingested 12 mothballs ... cytology board review with dr. sturgis https://gmtcinema.com

Naphthalene, 1-Methylnapthalene, 2-Methylnapthalene Toxic …

Witryna9 kwi 2024 · Due to the ubiquitous environmental existence, persistent organic pollutants (POPs) and their harmful effects have drawn attention among scientific communities. This chapter particularly emphasizes the mechanistic toxicity pathways of POPs when interacting with... Witryna19 cze 2024 · @article{osti_1529177, title = {Metabolic Mechanisms of Naphthalene Toxicity in Lung}, author = {Buchholz, Bruce A.}, abstractNote = {The objective of this … Witryna19 mar 2024 · Naphthalene, a Polycyclic Aromatic Hydrocarbon is widely used as a fumigant and disinfectant despite its toxic effect and is ranked as the ninth most threatening compound. bing chat helper

Biotransformation - an overview ScienceDirect Topics

Category:Naphthalene C10H8 - PubChem

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Naphthalene mechanism of toxicity

Characterisation of the toxic metabolite(s) of naphthalene

Witryna萘在啮齿类动物中的毒性已归因于反应性代谢物萘-1,2-氧化物（NPO），1,2-萘醌（1,2-NPQ）和1,4-萘醌（1,4-NPQ）。这些反应性代谢物在不同物种中形成的差异可以阐明萘发挥毒性的机制。蛋白质加合物使研究者能够研究无法直接测量的反应性代谢产物的分布。我们测量了雄性Swiss Webster小鼠血液中血红 ...

Naphthalene mechanism of toxicity

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WitrynaNaphthalene is a white solid substance with a strong smell. Poisoning from naphthalene destroys or changes red blood cells so they cannot carry oxygen. This … Witryna20 paź 2024 · Mechanism of toxicity is the study of how chemical or physical agents interact with living organisms that may trigger perturbations in cell function and/or structure or that may initiate repair mechanisms at the molecular, cellular, and/or tissue levels. Apoptosis, or programmed cell death, is a tightly controlled, organized process …

WitrynaNaphthalene. Contents. 1 Background. 1.1 Mechanism of toxicity; 2 Clinical Features; 3 Differential Diagnosis; 4 Evaluation; 5 Management; 6 Disposition; 7 References; … WitrynaNaphthalene is a white solid that evaporates easily. Fuels such as petroleum and coal contain naphthalene. It is also called white tar, and tar camphor, and has been used …

Witryna4.2 High risk circumstance of poisoning Naphthalene poisoning has occurred mostly in children who suck or chew mothballs (Hayes, 1982; Chun et al., 1998; Santucci & Shah, 2000). With the exception of dermatitis due to hypersensitivity with positive patch tests, reports of naphthalene poisoning in industry are rare (Gosselin et al., 1984). WitrynaNaphthalene. As little as 250–500 mg may produce hemolysis in a patient with G6PD deficiency. The amount necessary to produce lethargy or seizures is not known but …

Witryna1 lut 2024 · Naphthalene is metabolized in the liver and is oxidized to alpha-naphthol and other metabolites. The cytochrome P450 enzymes are capable of catalyzing these metabolic transformation reactions.

WitrynaNaphthalene. As little as 250–500 mg may produce hemolysis in a patient with G6PD deficiency. The amount necessary to produce lethargy or seizures is not known but … bing chat history extension edgeWitryna1 cze 2014 · The ionic mechanism of lead toxicity occurs mainly due to the ability of lead metal ions to replace other bivalent cations like Ca 2+, Mg 2+, Fe 2+ and … bing chat homepageWitrynaNaphthalene is released to the air from the burning of coal and oil and from the use of mothballs. Coal tar production, wood preserving, and other industries release small … cytology brush ifuWitryna1-Naphthaleneacetic acid ( NAA) is an organic compound with the formula C 10 H 7 CH 2 CO 2 H. This colorless solid is soluble in organic solvents. It features a carboxylmethyl group (CH 2 CO 2 H) linked to the "1-position" of naphthalene . bing chat history edgeWitrynaNaphthalene (91-20-3) is a component of crude oil and is found in petroleum-derived fuels and consumer products. The most common use of naphthalene in consumer … cytology book for medical studentsWitrynaBackground: Naphthalene ingestion and skin or inhalational exposure (accidental or deliberate) is an under-recognized cause of a severe toxidrome in regions where it is … cytology book pdfWitrynaIf urine flow declines, intravenous infusions must be carefully monitored to avoid fluid overload. Institute hemodialysis. Consider charcoal hemoperfusion in tandem to extract naphthalene and end-products. If anemia is severe, blood transfusions may be needed. Hydrocortisone may be of some benefit if significant hemolysis is present. /Fumigant ... bing chat home page